Epidermal advance agency (epidermal advance factor, EGF) is a baby peptide, and is composed of 53 amino acerbic residues, is a affiliate of the ample ancestors of chic EGF, is a multifunctional advance agency in vitro and in vivo for a array of tissue the corpuscle has a able mitogenic effect. EGF aforementioned acknowledgment specific corpuscle apparent receptor binding, in accordance with Sri Lanka. Novo United States - walking in the beginning of biomedical adorableness A10 documented, already combined, they advance receptor dimerization and phosphorylation to cytoplasmic sites. Activated receptor with at atomic 5 kinds of proteins with altered arresting sequences binding, arresting transduction, adjustment aftereffect on protein amalgam at the adaptation level. In addition, EGF may access intracellular DNA topoisomerase activity, but aswell advance the admeasurement gene expression, such as myc, fos, and so on.
A array of cells, such as epidermal advance agency to activate the covering and endoderm agent of corneal epithelial and endothelial cells, epidermis, bark band of beef (fibroblasts), mammary acini and stromal cells, its admeasurement and migration, to advance metabolism, derma awakening effect.
EGF can advance the DNA, RNA and protein biosynthesis function, can advance the amalgam of extracellular macromolecules (such as hyaluronic acid, adaptable fiber, protein, etc.), access in derma damp content, thereby accretion the animation of the skin, moisturizing the skin. Recombinant animal epidermal advance factor.
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From: Biochemical Reagent
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