Where to get NF-κB (human p50/p65) Combo Transcription Factor Assay Kit?

The NF-κB/Rel family of transcription factors is comprised of several structurally-related proteins that form homodimers and heterodimers and include p50/p105, p52/p100, RelA (p65), and c-Rel/NF-?B. Acting as dimers, these transcription factors bind to ?B sites on DNA, thereby regulating expression of target genes. The most common Rel/NF-?B dimer in mammals contains p50-RelA (p50/p65) heterodimers and is an attractive target for potential therapeutics in human inflammation and certain other diseases. Cayman`s NF-?B (human p50/p65) Combo Transcription Factor Assay is a non-radioactive, sensitive method for detecting specific transcription factor DNA binding activity in nuclear extracts. A specific double stranded DNA (dsDNA) sequence containing the NF-kB response element is immobilized onto the wells of a 96-well plate. NF-κB contained in a nuclear extract, binds specifically to the NF-?B response element. NF-?B p50 and p65 are detected by addition of specific primary antibodies directed against either NF-?B p50 or p65. A secondary antibody conjugated to HRP is added to provide a sensitive colorimetric readout at 450 nm.
Application/Transcription Factor Assay, Chemical Class/Assay Kits, Chemical Class/NF-?B
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Why should we use 2,3-Butanediol?

2,3-Butanediol is a colorless crystalline solid or viscous. Miscible with water, soluble in alcohol      and ether.2, 3 - butanediol can be used as hygroscopic agents, plasticizers and coupling agents. 2,3 - butanediol is also used as solvents and synthetic materials resin.It is used for the preparation of resin and used as a solvent, etc.2,3-Butanediol  a chemical compound composed of carbon, hydrogen, andoxygen. Its formula is C4H10O2. It is one of the constitutional isomers ofbutanediol. The 2R,3R stereoisomer of 2,3-butanediol is produced by a variety of microorganisms, in a process known as butanediol fermentation. It is found in cocobutter and in the roots of Ruta graveolens. It is used in the resolution of carbonyl compounds in gas chromatography.  For 2,3-Butanediol  fermentation ,which produces smaller amounts of acid than mixed acid fermentation, and butanediol, ethanol,CO2 and H2 are the end products. While equal amounts of CO2 and H2 are created during mixed acid fermentation, butanediol fermentation produces more than twice the amount of CO2 because the gases are not produced only by formate hydrogen lyase like they are in the mixed acid fermentation.

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